Like poisonous frogs, neotropical toads secrete a venom when irritated or threatened. The venom of this toad is cardiotoxic, disrupting normal heart. rhythms if ingested or introduced in the blood stream. If simply touched, the victim suffers from stinging, burning, and numbness in the exposed area for 1-6 hours. If this is a hand, nothing can be held for that period of time due to irritation.
A poisoned victim must make a saving throw for each round of contact with the toad, with a -2 penalty if the poison is introduced into an open wound, swallowed, or delivered via an envenomed weapon. If this saving throw is failed, the victim suffers from tightness in the chest, convulsions, salivation, and seizures, followed by death in 1-4 minutes. A successful
save indicates only irritation as outlined above.