Hiya!
How would you fine people play a person with aspurgers and/or autism?
along these lines:how would you fine people BUILD a person with aspurgers/autism?
Depending on the severity, just a simple adjustment to certain Skill rolls and maybe some bonus to a particular Skill.
For example, maybe -2 to Animal Handling, Insight, Perception, and all Charisma Skills....but, give that particular PC an "Expertise" (like the Thief ability) AND Advantage on all Animal Handling (Bovines). Other than that, I'd leave it up to the Player to role-play it all.
My reasoning comes from me being a single father to an autistic daughter (she just turned 11). She's a great kid, with her late mothers 'quirkiness' and funny-bone, but she is definitely lacking in the Animal Handling, Insight, Perception, Persuasion, etc skills to be sure! Schooling isn't really her thing, but in it she is very good at reading, math and languages. She is also rather amazing at remembering something she is told; her magic number is "3". When I showed her the ASL signs for "I love you", the first time she saw me do it she was confused. Then, right after I showed her again, she tried to mimic it. Then I showed/corrected her the third time. She had it memorized. A few months later, I got her attention, and Signed "I love you"...she immediately repeated it as I signed it. But she can do that with just about anything. She, for example, reads the song list on a CD case. I can then say "Corbyn, what's the 5th song, of Poison, on their Look What the Cat Dragged in CD? And she'll tell me.
BUT...I ask her what she did today at school? Pfft! Forget about it. She'll give the same general response every time, with no specifics.
So, yeah, penalties to some skill(s), big bonus to one or two others, and leave the rest up to roleplaying.
^_^
Paul L. Ming